USP or DSP technician in Bio production (F/M/X)

Role Summary

Context

Within the production team, and under the responsibility of the team leader, you will join a bioproduction unit operating according to GMP (GMP) standards. You will work on USP (cell culture) and/or DSP (recombinant protein purification) activities, within an environment with high quality requirements using "single-use" technologies.

Responsibilities

1. Preparation of production activities (USP & DSP)

• Qualification/preparation of equipment and verification of the availability of materials, buffers, consumables and assemblies.
• Writing and management of manufacturing recipes in a computerized system (parameters, sequences, durations, temperature instructions, etc.).
• Implementation of “single-use” production kits.
• Organization and storage of the area in compliance with GMP/GMP and internal procedures.
• Participation in line emptying, cleaning and first level maintenance of areas and equipment.

1. Carrying out USP activities (if cell culture assignment)

• Aseptic handling in a laminar flow hood.
• Amplification of cultures (flasks, wave bags).
• Inoculation and monitoring of 200–2000 L bioreactors.
• Batch clarification and end of cultivation management.
• Creation of cell banks.

1. Carrying out DSP activities (if purification assignment)

• Conducting manual purification operations or via automated recipes.
• Implementation of chromatography, depth filtration, TFF (tangential filtration) or dialysis activities.
• Cleaning, conditioning and preparation of chromatography columns.

1. Monitoring, documentation and quality

• Rigorous traceability in batch files and quality systems.
• Worksheet review and post-activity review.
• Opening and monitoring of deviations if necessary.
• Compilation of data and participation in technical investigations.

1. Schedules and organization

• Morning/afternoon rotational work.
• Punctual duty on weekends and possible on-call depending on production needs.

Requirements

Profile sought (USP/DSP common criteria)

Training

• Bac +2/3: BTS/DUT/Professional license in biotechnology, microbiology, chemistry, process engineering, pharmaceuticals or agri-food.
• 1 to 3 years of experience in biotechnology production, cell culture or purification (small or large scale).

Technical skills

• Knowledge of biotechnologies and/or the production of recombinant proteins.
• Good understanding of a GMP environment and aseptic constraints.
• Proficiency or familiarity with single-use equipment.
• Comfortable with computerized systems (MES, recipe writing).
• For USP: suitability for sterile handling.
• For DSP: knowledge of purification techniques (chromato, TFF, etc.).

Personal qualities

• A hands-on person, rigorous, dynamic, curious.
• Good team spirit and sense of communication.
• Ability to follow a schedule and contribute to meeting production deadlines.

HSE

• Strict compliance with safety instructions, wearing PPE, waste management.
• Proactive reporting of risk situations and participation in continuous improvement.

Benefits

• All your information will be kept confidential according to EEO guidelines.
• AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled.
• US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html
• US & Puerto Rico applicants seeking reasonable accommodation, click here to learn more:
• https: //www.abbvie.com/join-us/reasonable-accommodations.html

About the Company

AbbVie is committed to providing innovative, safe and effective medicines and products that address critical health issues and make a remarkable impact on people's lives. As a Global Trade Compliance organization, we are committed to promoting and innovating best-in-class trade compliance practices in a dynamic global environment.

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